Intracellular trafficking, localization and mobilization of platelet-borne thiol isomerases

OBJECTIVE: Thiol isomerases facilitate protein folding in the endoplasmic reticulum, and several of these enzymes, including PDI and ERp57, are mobilized to the surface of activated platelets, where they influence platelet aggregation, blood coagulation and thrombus formation. In this study we exami...

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Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Crescente, Marilena, Pluthero, Fred G., Li, Ling, Lo, Richard W., Walsh, Tony G., Louriero, Silvia, Ali, Marfoua S, Vaiyapuri, Sakthivel, Schenk, Michael P., Holbrook, Lisa M, Falet, Hervé, Jones, Ian M., Poole, Alastair W., Kahr, Walter H. A., Gibbins, Jonathan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407363/
https://ncbi.nlm.nih.gov/pubmed/27079884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307461
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