Estrogen Protection Against Mitochondrial Toxin-Induced Cell Death In Hippocampal Neurons: Antagonism by Progesterone

Previously we demonstrated that mitochondrial dysfunction plays a critical role in the pathogenesis of Alzheimer’s disease. Further, we have shown that the neuroprotective effects of 17β-estradiol (E2) are dependent upon mitochondrial function. In the current study, we sought to identify mitochondri...

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Hauptverfasser: Yao, Jia, Chen, Shuhua, Cadenas, Enrique, Brinton, Roberta Diaz
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200366/
https://ncbi.nlm.nih.gov/pubmed/21134358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.11.090
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