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Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Specific Clock Genes in the Mouse Cerebral Cortex

We have previously demonstrated that clock genes contribute to the homeostatic aspect of sleep regulation. Indeed, mutations in some clock genes modify the markers of sleep homeostasis and an increase in homeostatic sleep drive alters clock gene expression in the forebrain. Here, we investigate a po...

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Main Authors: Mongrain, Valérie, La Spada, Francesco, Curie, Thomas, Franken, Paul
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200344/
https://ncbi.nlm.nih.gov/pubmed/22039518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026622
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