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Robust mechanosensing and tension generation by myosin VI

Myosin VI is a molecular motor that is thought to function as both a transporter and a cytoskeletal anchor in vivo. Here we use optical tweezers to examine force generation by single molecules of myosin VI under physiological nucleotide concentrations. We find that myosin VI is an efficient transpor...

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Main Authors: Chuan, Peiying, Spudich, James A., Dunn, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200311/
https://ncbi.nlm.nih.gov/pubmed/20970430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.010
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