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Fingolimod provides long-term protection in rodent models of cerebral ischemia

OBJECTIVE: The sphingosine-1-phosphate receptor agonist fingolimod (FTY720), that has shown efficacy in advanced multiple sclerosis clinical trials, decreases reperfusion injury in heart, liver and kidney. We therefore tested the therapeutic effects of fingolimod in several rodent models of focal ce...

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Detalhes bibliográficos
Main Authors: Wei, Ying, Yemisci, Muge, Kim, Hyung-Hwan, Yung, Lai Ming, Shin, Hwa Kyoung, Hwang, Seo-Kyoung, Guo, Shuzhen, Qin, Tao, Alsharif, Nafiseh, Brinkmann, Volker, Liao, James K., Lo, Eng H., Waeber, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200194/
https://ncbi.nlm.nih.gov/pubmed/21280082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22186
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