The Soluble Guanylate Cyclase Stimulator BAY 41-2272 Inhibits Vascular Smooth Muscle Growth through the cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase Pathways

Vascular smooth muscle (VSM) proliferation and migration are key components in vessel remodeling. Cyclic nucleotide signaling is protective and has long-served as a therapeutic target against undesired VSM growth. The present work analyzed the effects of the soluble guanylate cyclase (sGC) stimulato...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Joshi, Chintamani N., Martin, Danielle N., Fox, Jonathan C., Mendelev, Natalia N., Brown, Trisha A., Tulis, David A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Cardiovascular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199990/
https://ncbi.nlm.nih.gov/pubmed/21825001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.183400
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares