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Activated G Protein α(s) Subunits Increase the Ethanol Sensitivity of Human Glycine Receptors

It is well known that ethanol modulates the function of the Cys loop ligand-gated ion channels, which include the inhibitory glycine receptors (GlyRs). Previous studies have consistently shown that transmembrane and extracellular sites are essential for ethanol actions in GlyRs. In addition, recent...

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Detalhes bibliográficos
Main Authors: Yévenes, Gonzalo E., Moraga-Cid, Gustavo, Romo, Ximena, Aguayo, Luis G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199981/
https://ncbi.nlm.nih.gov/pubmed/21821696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.184408
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