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Adenylyl Cyclase type 3, a marker of primary cilia, is reduced in primary cell culture and in lumbar spinal cord in situ in G93A SOD1 mice

BACKGROUND: The primary cilium is a solitary organelle important in cellular signaling, that projects from the cell surface of most growth-arrested or post-mitotic cells including neurons in the central nervous system. We hypothesized that primary cilial dysfunction might play a role in the pathogen...

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Main Authors: Ma, Xiaoxing, Peterson, Randy, Turnbull, John
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199874/
https://ncbi.nlm.nih.gov/pubmed/21767396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-71
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