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Allosteric Communication in Cysteinyl tRNA Synthetase: A NETWORK OF DIRECT AND INDIRECT READOUT

Protein structure networks are constructed for the identification of long-range signaling pathways in cysteinyl tRNA synthetase (CysRS). Molecular dynamics simulation trajectory of CysRS-ligand complexes were used to determine conformational ensembles in order to gain insight into the allosteric sig...

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Autori principali: Ghosh, Amit, Sakaguchi, Reiko, Liu, Cuiping, Vishveshwara, Saraswathi, Hou, Ya-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199515/
https://ncbi.nlm.nih.gov/pubmed/21890630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246702
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