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Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase

Cysteinyl-tRNA synthetase (CysRS) is highly specific for synthesis of cysteinyl adenylate, yet does not possess the amino acid editing activity characteristic of many other tRNA synthetases. To elucidate how CysRS is able to distinguish cysteine from non-cognate amino acids, crystal structures of th...

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Autors principals: Newberry, Kate J., Hou, Ya-Ming, Perona, John J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC126036/
https://ncbi.nlm.nih.gov/pubmed/12032090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.11.2778
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