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Structural Switching of Staphylococcus aureus Clp Protease: A KEY TO UNDERSTANDING PROTEASE DYNAMICS

ATP-dependent Clp protease (ClpP) is an attractive new target for the development of anti-infective agents. The ClpP protease consists of two heptameric rings that enclose a large chamber containing 14 proteolytic active sites. Recent studies indicate that ClpP likely undergoes conformational switch...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Jie, Ye, Fei, Lan, Lefu, Jiang, Hualiang, Luo, Cheng, Yang, Cai-Guang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199504/
https://ncbi.nlm.nih.gov/pubmed/21900233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.277848
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