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A Pilot Study of Bacterial Genes with Disrupted ORFs Reveals a Surprising Profusion of Protein Sequence Recoding Mediated by Ribosomal Frameshifting and Transcriptional Realignment

Bacterial genome annotations contain a number of coding sequences (CDSs) that, in spite of reading frame disruptions, encode a single continuous polypeptide. Such disruptions have different origins: sequencing errors, frameshift, or stop codon mutations, as well as instances of utilization of nontri...

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Bibliografski detalji
Glavni autori: Sharma, Virag, Firth, Andrew E., Antonov, Ivan, Fayet, Olivier, Atkins, John F., Borodovsky, Mark, Baranov, Pavel V.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199440/
https://ncbi.nlm.nih.gov/pubmed/21673094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr155
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