LPA-producing enzyme PA-PLA(1)α regulates hair follicle development by modulating EGFR signalling

Recent genetic studies of human hair disorders have suggested a critical role of lysophosphatidic acid (LPA) signalling in hair follicle development, mediated by an LPA-producing enzyme, phosphatidic acid-selective phospholipase A(1)α (PA-PLA(1)α, also known as LIPH), and a recently identified LPA r...

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Hlavní autoři: Inoue, Asuka, Arima, Naoaki, Ishiguro, Jun, Prestwich, Glenn D, Arai, Hiroyuki, Aoki, Junken
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199385/
https://ncbi.nlm.nih.gov/pubmed/21857648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.296
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