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Centrally mediated antinociceptive effects of cannabinoid receptor ligands in rat models of nociception

The endogenous nonapeptide hemopressin (HE) demonstrates potent block of the cannabinoid subtype-1 (CB1) receptor in vitro and robust antinociception in vivo. The current study evaluated the effects of centrally administered HE in mechanistically distinct pre-clinical rat models of pain—the hot plat...

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Autors principals: Hama, Aldric, Sagen, Jacqueline
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199362/
https://ncbi.nlm.nih.gov/pubmed/21958947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2011.09.004
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