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Effects of repeated dosing with mechanistically distinct antinociceptive ligands in a rat model of neuropathic spinal cord injury pain

A lack of efficacy of some analgesic drugs has been previously described in rats with neuropathic spinal cord injury (SCI) pain. It has been suggested that repeated dosing in these animals over time may eventually lead to efficacy. However, it is also possible that efficacy may diminish over time wi...

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Detalhes bibliográficos
Main Authors: Hama, Aldric T, Pearson, James P, Sagen, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184706/
https://ncbi.nlm.nih.gov/pubmed/25505583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.34
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