Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos

BACKGROUND: The tbx5 mutation in human causes Holt-Oram syndrome, an autosomal dominant condition characterized by a familial history of congenital heart defects and preaxial radial upper-limb defects. We report aberrant apoptosis and dormant cell growth over head, heart, trunk, fin, and tail of zeb...

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Bibliografiske detaljer
Main Authors:	Lu, Jenher, Tsai, Tzuchun, Choo, Sielin, Yeh, Shuyu, Tang, Renbing, Yang, Anhang, Lee, Hsinyu, Lu, Jennkan
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2011
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3199240/ https://ncbi.nlm.nih.gov/pubmed/21982178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-73
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Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos

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