A Human Head and Neck Squamous Cell Carcinoma Cell Line with Acquired cis-Diamminedichloroplatinum-Resistance Shows Remarkable Upregulation of BRCA1 and Hypersensitivity to Taxane

Recently, an inverse relationship between resistance to platinum-based chemotherapeutic agents and taxanes has been implicated in breast and ovarian cancers, and a possible pivotal role for BRCA1 has also been suggested. Because cis-diamminedichloroplatinum (CDDP) and taxanes are the most active ant...

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Bibliografische gegevens
Hoofdauteurs: Saiki, Yuriko, Ogawa, Takenori, Shiga, Kiyoto, Sunamura, Makoto, Kobayashi, Toshimitsu, Horii, Akira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2011
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199181/
https://ncbi.nlm.nih.gov/pubmed/22046189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/521852
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