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RNA interference in the clinic: challenges and future directions

Inherent difficulties with blocking many desirable targets using conventional approaches have prompted many to consider using RNA interference (RNAi) as a therapeutic approach. Although exploitation of RNAi has immense potential as a cancer therapeutic, many physiological obstacles stand in the way...

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Autores principales: Pecot, Chad V., Calin, George A., Coleman, Robert L., Lopez-Berestein, Gabriel, Sood, Anil K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199132/
https://ncbi.nlm.nih.gov/pubmed/21160526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2966
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