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TRPM7 ion channels are required for sustained phosphoinositide 3-kinase signaling in lymphocytes
Lymphocytes lacking the TRPM7 dual function ion channel/protein kinase exhibit a unique phenotype: they are unable to proliferate in regular media, but proliferate normally in media supplemented with 10–15 mM extracellular Mg(2+). Here, we have analyzed the molecular mechanisms underlying this pheno...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199037/ https://ncbi.nlm.nih.gov/pubmed/18590694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.06.002 |
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