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Structural features discriminate androgen receptor N/C terminal and coactivator interactions

Human androgen receptor (AR) transcriptional activity involves interdomain and coactivator interactions with the agonist-bound AR ligand binding domain (LBD). Structural determinants of the AR NH(2)- and carboxyl-terminal interaction between the AR NH(2)-terminal FXXLF motif and activation function...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Askew, Emily B., Minges, John T., Hnat, Andrew T., Wilson, Elizabeth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199032/
https://ncbi.nlm.nih.gov/pubmed/21664945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.03.026
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