Estradiol Promotes and Maintains Cumulus Cell Expression of Natriuretic Peptide Receptor 2 (NPR2) and Meiotic Arrest in Mouse Oocytes In Vitro

Natriuretic peptide type C (NPPC) and its cognate receptor natriuretic peptide receptor 2 (NPR2) are essential for maintaining meiotic arrest in mouse oocytes residing in Graafian follicles. Cumulus cells, which are associated with the oocyte, express the receptor NPR2, a guanylyl cyclase, whereas m...

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Autores principales: Zhang, Meijia, Su, You-Qiang, Sugiura, Koji, Wigglesworth, Karen, Xia, Guoliang, Eppig, John J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2011
Materias:
Reproduction-Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199003/
https://ncbi.nlm.nih.gov/pubmed/21914782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1118
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