Catenation and knotting of duplex DNA by type 1 topoisomerases: a mechanistic parallel with type 2 topoisomerases.

Escherichia coli omega protein, a type 1 topoisomerase, can catenate and knot duplex DNA circles. Previously, these activities were thought to be limited to type 2 topoisomerases. Catenation by omega requires a nick in one of the participating molecules, but it is not necessary that both be nicked....

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Brown, P O, Cozzarelli, N R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1981
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262776/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.843
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