LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs

BACKGROUND: Toll-like Receptor 3 (TLR3) detects viral dsRNA during viral infection. However, most natural viral dsRNAs are poor activators of TLR3 in cell-based systems, leading us to hypothesize that TLR3 needs additional factors to be activated by viral dsRNAs. The anti-microbial peptide LL37 is t...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lai, Yvonne, Adhikarakunnathu, Sreedevi, Bhardwaj, Kanchan, Ranjith-Kumar, C. T., Wen, Yahong, Jordan, Jarrat L., Wu, Linda H., Dragnea, Bogdan, Mateo, Lani San, Kao, C. Cheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198786/
https://ncbi.nlm.nih.gov/pubmed/22039520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026632
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