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LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs
BACKGROUND: Toll-like Receptor 3 (TLR3) detects viral dsRNA during viral infection. However, most natural viral dsRNAs are poor activators of TLR3 in cell-based systems, leading us to hypothesize that TLR3 needs additional factors to be activated by viral dsRNAs. The anti-microbial peptide LL37 is t...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198786/ https://ncbi.nlm.nih.gov/pubmed/22039520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026632 |
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