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Seesaw signal processing in pineal cells: homologous sensitization of adrenergic stimulation of cyclic GMP accompanies homologous desensitization of beta-adrenergic stimulation of cyclic AMP.

Studies of the adrenergic regulation of cyclic GMP in the pineal gland show that (-)-norepinephrine stimulates cyclic GMP primarily in pineal cells, rather than in nerve endings as previously thought. The response exhibits the interesting and unusual characteristic of homologous sensitization: It is...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Klein, D C, Auerbach, D A, Weller, J L
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6270688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4625
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