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Seesaw signal processing in pineal cells: homologous sensitization of adrenergic stimulation of cyclic GMP accompanies homologous desensitization of beta-adrenergic stimulation of cyclic AMP.

Studies of the adrenergic regulation of cyclic GMP in the pineal gland show that (-)-norepinephrine stimulates cyclic GMP primarily in pineal cells, rather than in nerve endings as previously thought. The response exhibits the interesting and unusual characteristic of homologous sensitization: It is...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Klein, D C, Auerbach, D A, Weller, J L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1981
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6270688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4625
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