The Minimal Domain of Adipose Triglyceride Lipase (ATGL) Ranges until Leucine 254 and Can Be Activated and Inhibited by CGI-58 and G0S2, Respectively

Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme of lipolysis. ATGL specifically hydrolyzes triacylglycerols (TGs), thereby generating diacylglycerols and free fatty acids. ATGL's enzymatic activity is co-activated by the protein comparative gene identification-58 (CGI-58) and inh...

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Autori principali: Cornaciu, Irina, Boeszoermenyi, Andras, Lindermuth, Hanna, Nagy, Harald M., Cerk, Ines K., Ebner, Catharina, Salzburger, Barbara, Gruber, Astrid, Schweiger, Martina, Zechner, Rudolf, Lass, Achim, Zimmermann, Robert, Oberer, Monika
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198459/
https://ncbi.nlm.nih.gov/pubmed/22039468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026349
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