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Rab5 GTPase controls chromosome alignment through Lamin disassembly and relocation of the NuMA-like protein Mud to the poles during mitosis

The small GTPase Rab5 is a conserved regulator of membrane trafficking; it regulates the formation of early endosomes, their transport along microtubules, and the fusion to the target organelles. Although several members of the endocytic pathway were recently implicated in spindle organization, it i...

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Autori principali: Capalbo, Luisa, D'Avino, Pier Paolo, Archambault, Vincent, Glover, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198372/
https://ncbi.nlm.nih.gov/pubmed/21987826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103720108
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