Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions

Cell motility is an essential process that depends on a coherent, cross-linked actin cytoskeleton that physically coordinates the actions of numerous structural and signaling molecules. The actin cross-linking protein, filamin (Fln), has been implicated in the support of three-dimensional cortical a...

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Bibliographic Details
Main Authors: Lynch, Christopher D., Gauthier, Nils C., Biais, Nicolas, Lazar, Andre M., Roca-Cusachs, Pere, Yu, Cheng-Han, Sheetz, Michael P.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198308/
https://ncbi.nlm.nih.gov/pubmed/21325628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0661
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