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The yeast Batten disease orthologue Btn1 controls endosome–Golgi retrograde transport via SNARE assembly

The human Batten disease gene CLN3 and yeast orthologue BTN1 encode proteins of unclear function. We show that the loss of BTN1 phenocopies that of BTN2, which encodes a retromer accessory protein involved in the retrieval of specific cargo from late endosomes (LEs) to the Golgi. However, Btn1 local...

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Bibliografski detalji
Glavni autori: Kama, Rachel, Kanneganti, Vydehi, Ungermann, Christian, Gerst, Jeffrey E.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198160/
https://ncbi.nlm.nih.gov/pubmed/21987636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102115
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