APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice

OBJECTIVE: Insulin stimulates both nitric oxide (NO)-dependent vasodilation and endothelin-1 (ET-1)–dependent vasoconstriction. However, the cellular mechanisms that control the dual vascular effects of insulin remain unclear. This study aimed to investigate the roles of the multidomain adaptor prot...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Wang, Yi, Cheng, Kenneth K.Y., Lam, Karen S.L., Wu, Donghai, Wang, Yu, Huang, Yu, Vanhoutte, Paul M., Sweeney, Gary, Li, Yiming, Xu, Aimin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2011
Konular:
Complications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198090/
https://ncbi.nlm.nih.gov/pubmed/21926268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0666
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller