The Epidermal Growth Factor Receptor Promotes Glomerular Injury and Renal Failure in Rapidly Progressive Crescentic Glomerulonephritis; the Identification of Possible Therapy

Rapidly progressive glomerulonephritis (RPGN) is a clinical a morphological expression of severe glomerular injury. Glomerular injury manifests as a proliferative histological pattern (“crescents”) with accumulation of T cells and macrophages, and proliferation of intrinsic glomerular cells. We show...

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Autori principali: Bollée, Guillaume, Flamant, Martin, Schordan, Sandra, Fligny, Cécile, Rumpel, Elisabeth, Milon, Marine, Schordan, Eric, Sabaa, Nathalie, Vandermeersch, Sophie, Galaup, Ariane, Rodenas, Anita, Casal, Ibrahim, Sunnarborg, Susan W, Salant, David J, Kopp, Jeffrey B., Threadgill, David W, Quaggin, Susan E, Dussaule, Jean-Claude, Germain, Stéphane, Mesnard, Laurent, Endlich, Karlhans, Boucheix, Claude, Belenfant, Xavier, Callard, Patrice, Endlich, Nicole, Tharaux, Pierre-Louis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198052/
https://ncbi.nlm.nih.gov/pubmed/21946538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2491
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