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Invariant NKT Cell Defects in Vitamin D Receptor Knockout Mice Prevents Experimental Lung Inflammation
Vitamin D receptor (VDR) deficiency (knockout, KO) results in a failure of mice to generate an airway hyper-reactivity (AHR) response on both the Balb/c and C57BL/6 background. The cause of the failed AHR response is the defective population of iNKT cells in the VDR KO mice since wildtype (WT) iNKT...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197972/ https://ncbi.nlm.nih.gov/pubmed/21948983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101519 |
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