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Invariant NKT Cell Defects in Vitamin D Receptor Knockout Mice Prevents Experimental Lung Inflammation

Vitamin D receptor (VDR) deficiency (knockout, KO) results in a failure of mice to generate an airway hyper-reactivity (AHR) response on both the Balb/c and C57BL/6 background. The cause of the failed AHR response is the defective population of iNKT cells in the VDR KO mice since wildtype (WT) iNKT...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu, Sanhong, Zhao, Jun, Cantorna, Margherita T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197972/
https://ncbi.nlm.nih.gov/pubmed/21948983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101519
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