IL-33 expands suppressive CD11b(+) Gr-1(int) and regulatory T cells (Treg), including ST2L(+) Foxp3(+) cells, and mediates Treg-dependent promotion of cardiac allograft survival

IL-33 administration is associated with facilitation of Th type-2 (Th2) responses and cardioprotective properties in rodent models. However, in heart transplantation, the mechanism by which IL-33, signaling through ST2L, the membrane-bound form of ST2, promotes transplant survival is unclear. We rep...

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Detalhes bibliográficos
Main Authors: Turnquist, Hēth R., Zhao, Zhenlin, Rosborough, Brian R., Liu, Quan, Castellaneta, Antonino, Isse, Kumiko, Wang, Zhiliang, Lang, Megan, Stolz, Donna Beer, Zheng, Xin Xiao, Demetris, A. Jake, Liew, Foo Y., Wood, Kathryn J., Thomson, Angus W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197898/
https://ncbi.nlm.nih.gov/pubmed/21949025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100519
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