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Lambda Exonuclease Digestion of CGG Trinucleotide Repeats
Fragile X syndrome and other triplet repeat diseases are characterized by an elongation of a repeating DNA triplet. The ensemble-averaged lambda exonuclease digestion rate of different substrates, including one with an elongated FMR1 gene containing 120 CGG repeats, was measured using absorption and...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197802/ https://ncbi.nlm.nih.gov/pubmed/19562332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-009-0502-5 |
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