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Lambda Exonuclease Digestion of CGG Trinucleotide Repeats

Fragile X syndrome and other triplet repeat diseases are characterized by an elongation of a repeating DNA triplet. The ensemble-averaged lambda exonuclease digestion rate of different substrates, including one with an elongated FMR1 gene containing 120 CGG repeats, was measured using absorption and...

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Detalhes bibliográficos
Main Authors: Conroy, R.S., Koretsky, A.P., Moreland, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197802/
https://ncbi.nlm.nih.gov/pubmed/19562332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-009-0502-5
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