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Protein Interaction-Based Genome-Wide Analysis of Incident Coronary Heart Disease

BACKGROUND: Network-based approaches may leverage genome-wide association (GWA) analysis by testing for the aggregate association across several pathway members. We aimed to examine if networks of genes that represent experimentally determined protein-protein interactions are enriched in genes assoc...

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Detalhes bibliográficos
Main Authors: Jensen, Majken K., Pers, Tune H., Dworzynski, Piotr, Girman, Cynthia J., Brunak, Søren, Rimm, Eric B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197770/
https://ncbi.nlm.nih.gov/pubmed/21880673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.960393
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