Multilocus Heterozygosity and Coronary Heart Disease: Nested Case-Control Studies in Men and Women

BACKGROUND: Generalized allelic heterozygosity has been proposed to improve reproductive fitness and has been associated with higher blood pressure, but its association with chronic disease is not well characterized. METHODS: Using the Affymetrix Genome-Wide Human 6.0 array, we performed whole genom...

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Bibliographic Details
Published in:PLoS One
Main Authors: Mukamal, Kenneth J., Jensen, Majken K., Pers, Tune H., Pai, Jennifer K., Kraft, Peter, Rimm, Eric B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430477/
https://ncbi.nlm.nih.gov/pubmed/25970579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124847
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