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A Simple, Direct Conjugation of Bacterial O-SP–Core Antigens to Proteins: Development of Cholera Conjugate Vaccines
Bacterial O-SP–core antigens can be conjugated to proteins in the same, simple way as synthetic, linker-equipped carbohydrates by applying squaric acid chemistry. Introduction of spacers (linkers) to either O-SP–core antigens or protein carriers, which is involved in commonly applied protocols, is n...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197769/ https://ncbi.nlm.nih.gov/pubmed/21899371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc2001984 |
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