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PERICYTE DEFICIENCIES LEAD TO ABERRANT TUMOR VASCULARIZATON IN THE BRAIN OF THE NG2 NULL MOUSE

Tightly-regulated crosstalk between endothelial cells and pericytes is required for formation and maintenance of functional blood vessels. When the NG2 proteoglycan is absent from pericyte surfaces, vascularization of syngeneic tumors growing in the C57Bl/6 mouse brain is aberrant in several respect...

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Autores principales: Huang, Feng-Ju, You, Weon-Kyoo, Bonaldo, Paolo, Seyfried, Thomas N., Pasquale, Elena B., Stallcup, William B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197744/
https://ncbi.nlm.nih.gov/pubmed/20599895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.06.023
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