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Near-Native Protein Loop Sampling Using Nonparametric Density Estimation Accommodating Sparcity
Unlike the core structural elements of a protein like regular secondary structure, template based modeling (TBM) has difficulty with loop regions due to their variability in sequence and structure as well as the sparse sampling from a limited number of homologous templates. We present a novel, knowl...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197639/ https://ncbi.nlm.nih.gov/pubmed/22028638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002234 |
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