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An Amino Acid Packing Code for α-helical Structure and Protein Design

This work demonstrates that all packing in α-helices can be simplified to repetitive patterns of a single motif: the knob-socket. Using the precision of Voronoi Polyhedra/Deluaney Tessellations to identify contacts, the knob-socket is a 4 residue tetrahedral motif: a knob residue on one α-helix pack...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joo, Hyun, Chavan, Archana G., Phan, Jamie, Day, Ryan, Tsai, Jerry
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867301/
https://ncbi.nlm.nih.gov/pubmed/22426125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.004
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