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An Amino Acid Packing Code for α-helical Structure and Protein Design
This work demonstrates that all packing in α-helices can be simplified to repetitive patterns of a single motif: the knob-socket. Using the precision of Voronoi Polyhedra/Deluaney Tessellations to identify contacts, the knob-socket is a 4 residue tetrahedral motif: a knob residue on one α-helix pack...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867301/ https://ncbi.nlm.nih.gov/pubmed/22426125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.004 |
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