A Genetic Variant in the IL-17 Promoter Is Functionally Associated with Acute Graft-Versus-Host Disease after Unrelated Bone Marrow Transplantation

Interleukin IL-17 is a proinflammatory cytokine that has been implicated in the pathogenesis of various autoimmune diseases. The single nucleotide polymorphism (SNP), rs2275913, in the promoter region of the IL-17 gene is associated with susceptibility to ulcerative colitis. When we examined the imp...

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Autores principales: Espinoza, J. Luis, Takami, Akiyoshi, Nakata, Katsuya, Onizuka, Makoto, Kawase, Takakazu, Akiyama, Hideki, Miyamura, Koichi, Morishima, Yasuo, Fukuda, Takahiro, Kodera, Yoshihisa, Nakao, Shinji
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197629/
https://ncbi.nlm.nih.gov/pubmed/22028838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026229
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