Donor Heme Oxygenase-1 Promoter Gene Polymorphism Predicts Survival after Unrelated Bone Marrow Transplantation for High-Risk Patients

Heme oxygenase-1 (HO-1), an intracellular enzyme that catalyzes the degradation of heme into biliverdin, free iron, and carbon monoxide, exerts anti-inflammatory and cytoprotective effects against endothelial cell injury. The HO-1 promoter gene has one important single-nucleotide polymorphism (SNP)...

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Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Horio, Tomohiro, Morishita, Eriko, Mizuno, Shohei, Uchino, Kaori, Hanamura, Ichiro, Espinoza, J. Luis, Morishima, Yasuo, Kodera, Yoshihisa, Onizuka, Makoto, Kashiwase, Koichi, Fukuda, Takahiro, Doki, Noriko, Miyamura, Koichi, Mori, Takehiko, Nakao, Shinji, Takami, Akiyoshi
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072481/
https://ncbi.nlm.nih.gov/pubmed/32059452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020424
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