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IL-17RA Signaling Amplifies Antibody-Induced Arthritis

OBJECTIVE: To investigate the role of IL-17RA signaling in the effector phase of inflammatory arthritis using the K/BxN serum-transfer model. METHODS: Wild-type and Il17ra(−/−) mice were injected with serum isolated from arthritic K/BxN mice and their clinical score was recorded daily. Mice were als...

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Detalhes bibliográficos
Main Authors: Sadik, Christian D., Kim, Nancy D., Alekseeva, Elena, Luster, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197623/
https://ncbi.nlm.nih.gov/pubmed/22028860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026342
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