Subchronic Peripheral Neuregulin-1 Increases Ventral Hippocampal Neurogenesis and Induces Antidepressant-Like Effects

BACKGROUND: Adult hippocampal neurogenesis has been implicated in the mechanism of antidepressant action, and neurotrophic factors can mediate the neurogenic changes underlying these effects. The neurotrophic factor neuregulin-1 (NRG1) is involved in many aspects of brain development, from cell fate...

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Autori principali: Mahar, Ian, Tan, Stephanie, Davoli, Maria Antonietta, Dominguez-Lopez, Sergio, Qiang, Calvin, Rachalski, Adeline, Turecki, Gustavo, Mechawar, Naguib
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197569/
https://ncbi.nlm.nih.gov/pubmed/22028923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026610
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