Genetic evidence for an essential role of neuronally expressed IL-6 signal transducer gp130 in the induction and maintenance of experimentally induced mechanical hypersensitivity in vivo and in vitro

Tenderness and mechanical allodynia are key symptoms of malignant tumor, inflammation and neuropathy. The proinflammatory cytokine interleukin-6 (IL-6) is causally involved in all three pathologies. IL-6 not only regulates innate immunity and inflammation but also causes nociceptor sensitization and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Quarta, Serena, Vogl, Christian, Constantin, Cristina E, Üçeyler, Nurcan, Sommer, Claudia, Kress, Michaela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2011
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197546/
https://ncbi.nlm.nih.gov/pubmed/21951917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-73
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