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Elimination of cannibalistic denaturation by enzyme immobilization or inhibition

The cannibalistic denaturation of α-chymotrypsin (EC 3.4.21.1) around neutral pH can be eliminated by immobilization (insolubilization) of the enzyme or by inhibition by specific reversible inhibitors, but the high-pH denaturation cannot be. The denaturation of the immobilized enzyme at high pH foll...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Wu, Hua-Lin, Lace, Daniel A., Bender, Myron L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1981
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319738/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16593052/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4118
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