Changes in myofilament proteins, but not Ca(2+) regulation, are associated with a high-fat diet-induced improvement in contractile function in heart failure

Pathological conditions such as diabetes, insulin resistance, and obesity are characterized by elevated plasma and myocardial lipid levels and have been reported to exacerbate the progression of heart failure (HF). Alterations in cardiomyocyte Ca(2+) regulatory properties and myofilament proteins ha...

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Autori principali: Cheng, Y., Li, W., McElfresh, T. A., Chen, X., Berthiaume, J. M., Castel, L., Yu, X., Van Wagoner, D. R., Chandler, M. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
Soggetti:
Energetics and Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197361/
https://ncbi.nlm.nih.gov/pubmed/21765056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00440.2011
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