Changes in myofilament proteins, but not Ca(2+) regulation, are associated with a high-fat diet-induced improvement in contractile function in heart failure

Pathological conditions such as diabetes, insulin resistance, and obesity are characterized by elevated plasma and myocardial lipid levels and have been reported to exacerbate the progression of heart failure (HF). Alterations in cardiomyocyte Ca(2+) regulatory properties and myofilament proteins ha...

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Detalhes bibliográficos
Main Authors: Cheng, Y., Li, W., McElfresh, T. A., Chen, X., Berthiaume, J. M., Castel, L., Yu, X., Van Wagoner, D. R., Chandler, M. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Energetics and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197361/
https://ncbi.nlm.nih.gov/pubmed/21765056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00440.2011
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